Comparison of Raltitrexed Plus Oxaliplatinl and 5-Fluorouracil/Leucovorin Plus Oxaliplatinl in Treatment of Advanced Colorectal Carcinoma

Objective The aim of the study was to assess the effect and security of raltitrexed with oxaliplatinl in the treatment of advanced colorectal carcinoma. Methods Forty cases of advanced colorectal cancer were divided into two groups, 20 cases in group A were given intravenously raltitrexed 15 min drip with 3 mg/ m2 on day 1, oxaliplatinl 3-hour drip with 130 mg/m2 on day 1. The regimen was repeated every 3 weeks was a cycle. 20 cases in group B were given oxaliplatinl 130 mg/m2 over 3 hours infusion on day 1...