Relationship between the vascular endothelial growth factor and microvessel density of ovarian neoplasm and its clinic-pathology
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Graphical Abstract
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Abstract
Objective To explore the relationship between vascular endothelial growth factor (VEGF) and the microvessel density (MVD) of ovarian neoplasm. Methods Strept-Avidin-Birotin consplex(SABC) immunohistochemistry method was used to determine the expression of VEGF and MVD in 54 cases of ovarian malignant and controls. Results(1) The expression of VEGF and MDV in ovarian malignant was higher than that in ovarian benign neoplasm and normal control ( P <0.01). (2) MVD in liver metastasis was significantly hi...
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