Observation on the Eff icacy of Durogesic in Treatment of Sixty Patients with Moderate or Severe Pain

Objective 　To observe the response and adverse reactions of Durogesic ( Transdermal Fentanyl) in the t reatment of cancer patients with moderate or severe pain. Methods 　Sixty advanced cancer patients with moderate or severe cancer pain were treated with Durogesic. evaluated the pain relief degree according to Numerical Rating Scale (NRS) and investigated the quality of life by the score criterion of Quality of Life (QOL), and observed the adverse reactions. Results 　The pain remission rate in cancer patient s of this group was 98. 3 %, including excellent remission rate 41. 7 % and effective remission rate 51. 67 %.The main adverse actions were nausea and vomiting, constipation, and dizziness. Conclusion 　Durogesic has significant efficacy, and mild adverse reactions, it is a simple way to using Durogesic for relieving moderate or severe cancer pain. Durogesic can improve the quality of life markedly.