The Expressions of p53 、p21<sup>WAF1</sup> and p16 in the Gastric Precancerous Lesions and the Cancer

LAN Jing; XIONG Yong-yan; TIAN Su-fang; et al

doi:10.3971/j.issn.1000-8578.489

LAN Jing, XIONG Yong-yan, TIAN Su-fang, et al. The Expressions of p53 、p21WAF1 and p16 in the Gastric Precancerous Lesions and the Cancer[J]. Cancer Research on Prevention and Treatment, 2001, 28(06): 438-440. DOI: 10.3971/j.issn.1000-8578.489

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The Expressions of p53 、p21^WAF1 and p16 in the Gastric Precancerous Lesions and the Cancer

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Objective To investigate the expressions of p53?p21 WAF1 and p16 and their interrelationship in the gastric carcinogenesis. Methods The expressions p53?p21 WAF1 and p16 were detected by means of SP immunohistochemical staining in the 65 cases of chronic atrophy gastritis, 93 cases of intestinal metaplasia, 94 cases of gastric epithelia dysplasis, 60 cases of gastric carcinoma. Results With the development of the lesion,they were abnormal gradually( P <0.05),especially in the moderate, severe dysp...

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The Expressions of p53 、p21WAF1 and p16 in the Gastric Precancerous Lesions and the Cancer

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The Expressions of p53 、p21^WAF1 and p16 in the Gastric Precancerous Lesions and the Cancer