The effect of quercetinon the cell cyclein nudemice with transplantation tumor of breast carcinoma

Objective To study the effect of quercetin on the cell cycle in nude mice with transplantation tumor of breast carcinoma. Methods 24 nude mice with transplantation tumor of MCF 7 were randomized into 4 groups with six mice in each group: control group, quercetin group, adriamycin group and combining group. The cell cycle distribution of tumor was analysed by flow cytometry. The espression of cyclin D1 was detected by immunohistochemistry. Results The rate of phase G0/G1 on the whole cycle of control group...