Improving Chemotherapy Effect of HeLa Cells by Inhibiting PI3K/Akt Signal Transduction

Objective To explore the lethal effect role of the therapeutic alliance of inhibiting PI3K/Akt signal transduction and anticancer drugs in HeLa cells of cervix cancer. Methods Detect the inhibition ratio of celecoxib, DDP and docetaxel in Hela or associated with PI3K inhibitor-LY294002 by Mono-nuclear cell direct cytotoxicity assay (MTT). Detect the apoptosis ratio of Celecoxib, DDP and Docetaxel in Hela or associated with PI3K inhibitor-LY294002 by flow cytometer. Results 1. The inhibition ratio was enhanc...