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ZHANG Na, XIONG Yong-yan, LI Li. The Relationship between Expression of survivin,bcl-2,bax and Multidrug Resistance Gene in Non-small Cell Lung Cancer[J]. Cancer Research on Prevention and Treatment, 2006, 33(03): 168-170. DOI: 10.3971/j.issn.1000-8578.439
Citation: ZHANG Na, XIONG Yong-yan, LI Li. The Relationship between Expression of survivin,bcl-2,bax and Multidrug Resistance Gene in Non-small Cell Lung Cancer[J]. Cancer Research on Prevention and Treatment, 2006, 33(03): 168-170. DOI: 10.3971/j.issn.1000-8578.439
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The Relationship between Expression of survivin,bcl-2,bax and Multidrug Resistance Gene in Non-small Cell Lung Cancer

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  • Objective To investigate the expression of apoptosis proteins survivin,bcl-2, bax and the multidrug resistance(MDR)associated genes MDR1mRNA,MRPmRNA in non-small cell lung cancer(NSCLC),their relationship and significance. Methods The expression of MDR1mRNA and MRPmRNA in 113 NSCLC specimens were detected by in situ hybridization,and the expression of survivin,bcl-2 and bax in the same specimens were detected by immunohistochemistry. Results The positive rates of 113 NSCLC samples for MDR1 mRNA,MRP mRNA,survi...
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