Expression of PTEN in Colorectal Carcinoma
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Graphical Abstract
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Abstract
Objective To investigate the expression of PTEN in colorectal carcinoma and its relationship to invasion and metastasis. Methods SP immunohistochemical technique was used to assess the expression of PTEN, E-cad and MMP-2 in 67 cases of colorectal carcinoma. Five cases of normal colorectal tissues were served as control. Results The PTEN positive reaction was seen in cytoplasm. Compared with normal colorectal tissues, the expression of PTEN in the colorectal carcinoma was lower in both positive rate and inte...
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