High-Dose-Folinic Acid, 5-fluorouracil Bolus and Continuous Infusion 48 Hours Combined with Carboplatin in Advanced Esophageal Carcinona

Objective To assess the anti-tumor efficacy and safety of high-dose-folinic acid plus 5-fluorouracil bolus and continuous infusion 48 hours combined with carboplatin in treating advanced esophageal carcinoma. Methods 33 patients with advanced esophageal carcinoma were treated with high-dose-folinic acid plus 5-fluorouracil bolus and continuous infusion 48 hours combined with carboplatin. Results There were 3 complete respone, 12 partial respone, 17 no changes and 1 progressive disease in this series with to...