Inhibitory Effect of Suramin Combination with Quercetin on the Metastasis of Lung Adenocarcinoma in Mice
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Graphical Abstract
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Abstract
Objective To study the effect of Suramin combination with Quercetin on lung metastasis of lung aenocarcinoma LA795 in mice. Methods Forty T739 mice bearing high metastasis LA795 cells were randomized into five groups:control group, DDP group, Quercetin group, Suramin group, Quercetin + Suramin group.Different treatments were served from day 4 after transplantation and all mice were sacrificed after 24 days.Lung and Subcutaneous tumors were processed for histological examination.The metastatic tumor foci on l...
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