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TIAN Bin-qun, HU Li-quan, ZHENG Xin-min, . Effect of Gastric Juice on Bcl-2/Bax Expression of Human Bladder Cancer Cell Line[J]. Cancer Research on Prevention and Treatment, 2000, 27(01): 43-45. DOI: 10.3971/j.issn.1000-8578.329
Citation: TIAN Bin-qun, HU Li-quan, ZHENG Xin-min, . Effect of Gastric Juice on Bcl-2/Bax Expression of Human Bladder Cancer Cell Line[J]. Cancer Research on Prevention and Treatment, 2000, 27(01): 43-45. DOI: 10.3971/j.issn.1000-8578.329

Effect of Gastric Juice on Bcl-2/Bax Expression of Human Bladder Cancer Cell Line

  • Objective To study the mechanism of apoptosis induced by gastric juice. Methods Flow cytometry and immunohistochemistry were utilized to observe the effect of gastric juice on Bcl-2/Bax expression of human bladder cancer cell line BIU-87. Results After administration of gastric juice,AI increased,Bcl-2 expression reduce,Bax expression increased and Bcl-2/Bax ratio was 0.71. Conclusion It was suggested that gastric juice could induce the apoptosis of BIU-87 by reducing Bcl-2 and increasing Bax.
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