The role of dendritic cells mediated antitumor immunity in laryngeal cancer and precancerous lesions

Objective To study the role of DCs in tumor infiltraing T lymphocytes activation in precancerous lesions and carcinoma of the Larynx. Methods 39 specimens, histological diagnosis disclosed precancerous lesions of the larynx in 29 cases and in 10 cases, with squamous cell carcinoma, were performed using antibodies against the cell surface markers S-100? HLA-DR?CD45RO, CD45RA by immunohistochemisty. Results S-100+ cells could be detected in 9 of 10 cases in mild atypical hyperplasia. The infiltration of t...