Influence of aspirin on growth and NOS expression in astrocytoma cell line

Objective To investigate the effect of Aspirin on the proliferation and NOS expression in astrocytoma cell line, and probe into its mechanism . Methods The effect of Aspirin on the growth of astrocytoma cells was evaluated by MTT assay; NOS protein levels were determined by immunohistochemistry, NO and CEA concentration in the medium were determined by Griess assay and lepton catch immunising method respectively. Results Aspirin can inhibit the growth of astrocytoma cells, induce theexpressionofiNOS, incr...