Expression of Mucin MUC1 and MUC2 in Colorectal Adenocarcinoma and Their Clinical Significance
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Graphical Abstract
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Abstract
Objective To explore the relationship between expression of mucin MUC1 and MUC2 and clinicopathological parameters in colorectal adenocarcinoma and colorectal adenoma. Methods The expression of MUC1 and MUC2 were detected in 20 colorectal adenomas and 60 colorectal adenocarcinomas by immunohistochemical SP method. Results The positive expression rates of mucin MUC1 in 20 colorectal adenoma and 60 colorectal adenocarcinomas were 10% and 46.7%, but MUC2 were 100% and 58.3% respectively. The expression of...
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