Loss of Fragile Histidine Triad Protein Expression in Cervical Squamous Cell Carcinoma

Objective To investigate the expression of fragile histidine triad gene protein, FHIT and the possible relationship between FHIT expression and clinicopathological indices in cervical squamous cell carcinoma. Methods Detecting FHIT protein expression in 100 cervical squamous cell carcinomas, 83 para-neoplastic tissues and 10 normal cervical tissues and analysing its relationship to histological grade and clinical stage by SP immunohistochemical method. Results There was a significant difference in FHIT exp...