Effect of Erythropoietin on Chemotherapy-induced Anemia
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Graphical Abstract
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Abstract
Objective To investigate the prevention effect of erythropoietin on chemotherapy-induced anemia. Methods Mice were implanted with the S (180) sarcoma cells in the left hind groin subcutaneously. rHuEPO was injected subcutaneously before tumor implantation. 4 days before implantation, anemia was induced using a single dose of carboplatin. 5 days after tumor implantation, cyclophosphamide was injected intraperiton to treat the tumor. Blood cell parameters were assessed. Results At the time of CTX chemother...
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