Effect of dexamethasone on tumor growth and vascular endothelial growth factor expression in mouse H_(22) model

Objective To observe the effect of dexamethasone on tumor growth and vascular endothelial growth factor (VEGF) expression in mouse H ₂₂model. Methods H ₂₂ cells were inoculated subcutaneous into BALB/c mice. Intraperitoneal injection of dexamethasone began from the day inoculation. Diameters of tumor were measured every day. Tumor microvessel count was performed by immunohistochemical staining with anti-CD31 monoclonal antibody. Proliferation of H ₂₂ cells and ECV-304 cells (human umbilic...