Expression and significance of E-cadherin and CD44v6 in medullary breast carcinoma
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Graphical Abstract
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Abstract
Objective To study the mechanism of typical medullary carcinoma and atypical medullary carcinoma′s similar morphology and different prognosis . Methods The immunohistochemical staining method was used to evaluate the positivity of E cadhein,CD44v6 in 30 cases of atypicial medullary carcinoma and 18 cases of typicial medullary carcinoma. Results The staining intensity of E cadherin oncoprotein typical medullary carcinoma was significantly higher than those in atypical medullary carcinoma( P <0.05). T...
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