A Comparison of the Therapeutic Effects of Different Chemotherapy Regimens for Stage Ⅲ～Ⅳ non Small Cell Lung Cancer

Objective To evaluate the efficacy and toxicity of MVP(MMC+VDS+CDDP) regimen,MIC(MMC+IFO+CDDP)regimen and MNP(MMC+NVB+CDDP)regimen for stage Ⅲ～Ⅳ non-small-cell lung cancer (NSCLC). Methods The clinical data of 103 cases with stage Ⅲ～Ⅳ NSCLC were analysed.Of whom 36 cases were treated with MVP regimen,30 cases with MIC regimen,37 cases with MNP regimen. Results The result showed that respose rates of MVP,MIC and MNP regimen were 30.6% ，33.3% and 48.6% respectively.There was no statistical significant difference between them(P＞0.05).The major toxic reaction were tolerable myelo-supression and gastrointes-tinal tract reaction. Conclusion :MVP，MIC and MNP are effective and safe chemotherapy regimens and can be used as first-line regimen for treatment of stage Ⅲ～Ⅳ NSCLC Patients.