Expression of Human Papillomavirus Type 16 DNA in Human Breast Tissues
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Graphical Abstract
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Abstract
Objective To investigate the etiologic relationship between human papillomavirus (HPV) type 16 infection and human breast cancer. Methods In situ hybridization (ISH) technique was used to detect the expression of HPV type 16 DNA in 50 cases of breast cancer and 30 cases of normal breast tissues. Results ISH technique showed the positive rate of HPV type 16 DNA in cancer group and in normal group were 52% and 20.0%,respectively.HPV type 16 infection was confirmed in muliple breast cancer tissues types and main...
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