The effect of APBMV on human hepotoma cell line
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Graphical Abstract
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Abstract
Objective To obserne the effect of antineoplastic polypeptide from Buthus martensii venom (APBMV) on the human heptoma cells SMMC-7721. Methods Using the MTT colorimetric method, the growth-inhibiting test and the colony-formation inhibiting assay. Results The results revealed that APBMV had obvious cytotoxicity on SMMC-7721,1C50 was 11. 33μg/ml;APBMV could obviously inhibit the cellu- lar growth. There were obvious dose-response and timeresponse relationship. The IC50 we...
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