Evaluation of lymph node response to neoadjuvant chemotherapy in untreated nasopharyngeal carcinoma

Objective To evaluate the response and toxicity of neoadjuvant chemotherapy (Epirubicin plus DDP and 5-Fu) in patients with of nasopharynx carcinoma (NPC). Methods From April 1999 to August 2001, twenty-six patients with NPC (N 2 17, N 3 9; T 2 8,T 3 12,T 4 6 cases and no M 1) were treated with neoadjuvant chemotherapy consisting DDP (100mg/m 2 i.v. on Day 1), epirubicin (70 mg/m 2 i.v. on Day 1), and 5-Fu(1000mg/m 2 i.v. from day 1 to day 5), this regimen was repeated every 21 days. All patient...