The relationship between reactivity of telomerase and helicobacter pylori infection in different lesions of gastric mucosae

Objective To investigate the relationship between reactivity of catalytic protein submit of human telomerase reverse transcriptase (hTHER) and helicobacter pylori(Hp) infection. Methods Histochemical staining,immunohistochemistry and in situ hybridization were conducted to detect Hp infection and reactivity of hTERT in 42 chronic gastritis (CG), 81 intestinal metaplasia (IM), 75 gaseric epithelial dysplasia (GED) and 84 gastric carcinoma (GC). Results (1)The expression of hTERTmRNA increased with the devel...