Expression of integrin α_5β_1 and nm23 in breast cancer and their clinical significance

Objective To investigate the expression of integrin α 5β 1 and nm23 and their clinical significance in breast cancer and the correlation between them. Methods Expression of integrin α 5β 1 and nm23 was examined immunohistochemically in 51 cases of breast cancer and 10 cases of normal breast tissues. Results ① The low expression of integrin α 5β 1 in breast cancer tissues is associated with the metastasis of lymph nodes and the tissues low differentiation. ② The low expression of nm23 in breast canc...