A study on relationship between H.pylori infection and PCNA、bcl-2 expressions in different gastric mncosa lesions

Objective To study the relationship between Hp infection and gastric epithelial cell proliferation as well as apoptosis in different gastric mucosa lesions. Methods Hp infection?PCNA and bcl-2 expression?DNA content and aneuploidy of CAG?IM?GED and GC in 312 gastric specimens were detected by means of SP immunohischemical staining and image analysis. Results In Hp positive cases, positive rates and overexpression rates of PCNA and bcl-2 expressions in gastric carcinogenesis were progressively increased?O...