The Building and Evaluation of a Hypoxic -xenograft Animal Model of Human Cervical Cancer

Objective To bulid a hypoxic animal model of the xenograft of human cervical carcinoma, and to evaluate this model. Methods We injected 0.2 ml solution of Hela cells into the lateral skin of right hindlimb of each nude mouse. When the xenograft is large enough (about 1.7 cm) to have the trend of ulcer, the partial tension of oxygen in the tumor and normal tissue was measured with bi passage transductive needle of tissue PO 2. The routine pathological examination of the xenograft was done, and the H...