Expression of FHIT, Ki67 and bax and Clinical Significance in Cervix Carcinoma

Objective To investigate the expression of FHIT, Ki67 and bax and their relationship with clinicopathologic parameters and prognosis in cervix carcinoma. Methods Immunohistochemical analysis was performed in 50 invasive cervix carcinomas and 20 normal cervix tissues. Results Reduction or absence of FHIT expression was found in 52%(26/50)of the tumors. Positive staining of Ki67 was detected in 36 of 50 (72%) cervix carcinomas. Bax immunoreactivity was observed in 31 of 50 (62%) cervix carcinomas. Loss of FH...