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WEN ZHong, XIAO Jian-yun, TIAN Yong-quan, et al, . The role of telomere, telomerase and its hTR in nasopharyngeal carcinoma[J]. Cancer Research on Prevention and Treatment, 2002, 29(04): 298-300. DOI: 10.3971/j.issn.1000-8578.2369
Citation: WEN ZHong, XIAO Jian-yun, TIAN Yong-quan, et al, . The role of telomere, telomerase and its hTR in nasopharyngeal carcinoma[J]. Cancer Research on Prevention and Treatment, 2002, 29(04): 298-300. DOI: 10.3971/j.issn.1000-8578.2369
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The role of telomere, telomerase and its hTR in nasopharyngeal carcinoma

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  • Objective To explore the role of telomere, telomerase and its hTR in NPC. Methods The telomere kinetic, The expressions of telomerase and its hTR were studied with Southern Blot, TRAP PCR ELISA and RT nested-PCR, respectively. Results There were shorter MTL (4.5±2.3kb) and higher telomerase activity (88.0%) in nasopharyngeal tissues as compared with normal control. High expression of telomerase was also noticed in the adjacent tissues( 64.7%). Telomerase activities were also related to the late stage carc...
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