An ultrastructural and morphometric study on the effect of phosphorus-32 glass microspheres (~(32)P-GMS) on the human hepatocellular carcinoma in nude mice
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Graphical Abstract
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Abstract
Objective To study anticancer effect and ultrastructural influnce of 32 P-GMS injected to the hepatocellular carcinoma in nude mice. Methods The ultrastructural changes of tumor was examined by electron microscope and stereology . Results In treated group, a lot of tumor cells (35%~70%) were killed.Ultrastructurally,severe nuclear damage was observed in the death cells. Besides, well differentiated and degenerative tumor cells were seen.The skin and muscle neighboring to the t...
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