Effects on viability of Jurkat cell of novel cloned gene HC56,HC71 and HC90 mapped at human chromosome 17p13.3

Objective To investigate the effects on cell viability of T lymphoma cell line Jurkat of HC56, HC71 and HC90 mapped at human chromosome 17p13.3. Methods HC56, HC71 and HC90 gene were transfected into Jurkat cells respectively by the medium of liposome. The effects on cell viability of the exogenous gene products were observed by trypan blue dye exclusion test. Results The viability of Jurkat cells at 24, 48, 72 and 96 hours after HC56 and HC71 gene transfected was inhibited significantly( P <0.01) a...