Clinicopathologic Analysis of Strumal Carcinoid of Ovary

Objective 　To study the clinicopathologic characteristics of st rumal carcinoid of the ovary. Methods 　Four cases of st rumal carcinoid of the ovary were studied by clinical and pathological features, immunohistochemical staining, elect ron microscopy and clinical follow up, with review of related litera2 ture. Results 　Three cases were mixed type and 1 was the type of node in the cyst macroscopically. Three cases were t rabecular patterns and 1 of t rabecular pattern predominatly associated with island st ructure. Immunohistochemist ry showed 4 cases were positive for NSE and Syn, 3 for CgA and calcitonin, 1 for 52 HT ;positive for TG, TTF21 in the thyroid tissue and negative in the caicinoid. Conclusion 　St rumal car2 cinoid of the ovary is a low grade malignant neuroendocrine carcinoma with thyroid tissue.