Expression of FHIT in Colorectal Carcinoma and Its Relationship with PCNA and Caspase-3
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Graphical Abstract
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Abstract
Objective To study the expression of FHIT(fragile histidine triad) protein、Caspase-3、PCNA in sporadic colorectal carcinoma(SCC) and their clinical significance. Methods Immunohistochemistry SP method was used to determine the expression of FHIT,Caspase-3 and PCNA in surgically resection specimens of 92 SCC and 28 normal colorectal tissues. Results (1) The positive different expression of FHIT protein、Caspase-3、PCNA in normal colorectal tissues and SCC was statistically significant(P<(0.01)).(2) Expression o...
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