Relation of Interleukin-8 Expression with Angiogenesis in Human Oral Souamous Cell Carcinoma
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Graphical Abstract
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Abstract
Objective To explore the expression of interleukin-8(IL-8) and it s relation with angiogenesis and tumor biological behavior in human oral squamous cell carcinoma(OSCC). Methods The expression of IL-8 and the intratumoral microvessel density(iMVD) in 55 cases of human oral squamous cell carcinoma and 10 case of normal lingual mucosa were examined by means of immunohistochemical method. Results The positive staining for IL-8 was obtained in 32 cases of the OSCC((58.18%)),and iMVD was(38.58)±(12.43)/×400 in OSC...
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