Expression and significance of bcl-2 and p16 protein in esophageal squamous cell cancer and their surrounding tissues

Objective To study the expression and significance of bcl-2 and p16 in esophageal squamous cell cancer and the surrounding tissues. Methods S-P method was used to examine the expression of bcl-2 and p16 in 40 esophageal squamous cell cancer and the surrounding tissues. Results Expression of bcl-2 was 6%, 63.3%, 46.5% and 42.5% in normal esophageal mucosa, atypical hyperplasia, and squamous carcinoma tissues, respedively. There were significant differences between normal esophageal mucosa and ot...