Expression of NOS isozymes, VEGF and micro vessel density in 75 primary esophageal squamous cell carcinomas

Objective This study was to investigate the expression of different nitric oxide synthase isozymes(NOSII-III) and vascular endothelial growth factor in the primary esophageal squamous cell carcinomas. A further analysis was performed to correlate the immunohistochemical data with tumor angiogenesis and clinicopathologic features. Methods Surgical specimens from 75 primary esophageal squamous cell carcinomas were examined for iNOS,cNOS,VEGF expression and micro vessel density by immunocytochemical staini...