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FENG Zhen-bo, LU Zi-li, HE Ru-kun. Expression of ras oncogene p21 product and IGF-II in liver cirrhosis[J]. Cancer Research on Prevention and Treatment, 2003, 30(04): 270-272. DOI: 10.3971/j.issn.1000-8578.2263
Citation: FENG Zhen-bo, LU Zi-li, HE Ru-kun. Expression of ras oncogene p21 product and IGF-II in liver cirrhosis[J]. Cancer Research on Prevention and Treatment, 2003, 30(04): 270-272. DOI: 10.3971/j.issn.1000-8578.2263

Expression of ras oncogene p21 product and IGF-II in liver cirrhosis

  • Objective To probe the role of ras oncogene p21 product and IGF-II in the development of cirrhotic nodules and hepatocellular carcinoma(HCC). Methods S-P immunohistochemical technique was used to analyze the expression of p21 and IGF-II was studied in 50 cases of liver cirrhosis without HCC, 28 cases of precancerous liver cirrhotic tissues, and 22 HCC cases. Results The positive rates for p21 and IGF-II in cirrhosis with or without HCC were significantly higher than these for HCC (P< 0.05). The posit...
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