The effect of infusing thrombin into pleural cavity for treatment of malignant pleural effusion

Objective To evaluate the tierapeutic effects of infusing thrombin and combined bleomycin into pleural cavity for treatment of malignant pleural effusion. Methods the pleural effusion was drain out from a intrapleural catheter and then infused thrombin,thrombin+bleomycin and bleomycin inspectively and their therapeutic effects were compared in ramdomized trial. Results the response rate of the thrombin groups?the thrombin+bleomycin groups and bleomycin groups were 52.4%?90.5% and 71.4% respectively. Side-e...