Studies on the Confrontation of Thermo-chemotherapy of ADM on Human Multidrug -resistant Hepatocellular Carcinoma Cell Line

Objective To comparatively observe the effects of thermo-chemotherapy of ADM on human multidrug-resistant hepatocellular carcinoma cell line (7721/Adm) to sensitivity and intracellular concentration of ADM. Methods By means of water bath and MTT assay,the sensitivity of 7721/Adm to ADM was observed,and the effects of hyperthermia on intracellular concentration of ADM of 7721/Adm was detected by flow cytometry. Results (1) Cell line survive rates of 7721/Adm were 70.2%?40.8% after chemotherapy and thermo-che...