The Effect of Vascular Endothelial Growth Factor Expression on the Biological Characteristics of Human Gastric Cancer Cells

Objective To more directly establish the effect of vascular endothelial growth factor(VEGF)expression on the biological characteristics of human gastric cancer cells. Methods VEGF 165 sense and antisense gene expression vectors were introduced into human gastric cancer cells,respectively.Then cell cycle proliferative ability in vitro and growth in nude mice of transfected cells were examined. Results Cell cycle analysis showed that the number of transfected cells with antisense VEGF 165 gene had an ...