A study of relationship between telomerase activity and cyclin D_1 expression in gastric cancer tissue
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Graphical Abstract
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Abstract
Objective To explore the possible relationship between telomerase activation and cyclin D 1 in human gastric cancer tissue. Methods Telomerase activity was measured with Telomerase PCR-ELISA Kit (Boehringer Mannhei). Cyclin D 1 mRNA level was detected with RT-PCR ELISA. The 84 tissue samples of primary gastric cancer and its associated-cases were analyzed. Results The analysis of clinical sample displayed the progressing increase of cyclin D 1 overexpression level was found from gastric benign disea...
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