Expression of Cyclooxygenase-2 in Human Renal Cell Carcinoma
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Graphical Abstract
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Abstract
Objective To study the expression of cyclooxygenase 2 (COX 2) in human renal cell carcinomas(RCCs) and to evaluate its clinical significance. Methods The expression of COX 2 was observed in 35 RCCs by immunohistochemical staining of SP method. Results COX 2 specific proteins were found in 24 of 35 RCC specimens, while in control renal tissues were 4 of 20. Expression of COX 2 in RCCs was significantly higher than that in control renal tissues( P < 0.05 ). There are statistical significances between the PT...
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