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WU Feng-yun, LIU Yun-jiang. The Role of Cathepsin D on the Invasion and Metastases of Breast Cancer[J]. Cancer Research on Prevention and Treatment, 2004, 31(12): 730-732. DOI: 10.3971/j.issn.1000-8578.2065
Citation: WU Feng-yun, LIU Yun-jiang. The Role of Cathepsin D on the Invasion and Metastases of Breast Cancer[J]. Cancer Research on Prevention and Treatment, 2004, 31(12): 730-732. DOI: 10.3971/j.issn.1000-8578.2065
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The Role of Cathepsin D on the Invasion and Metastases of Breast Cancer

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    • Abstract
  • Objective To investigate the role of cathepsin D in facilitating tumor cells invasion and metastases by comparing cathepsin D expression with clinical and biological indicators in breast cancer. Methods By immunohistochemical SP method. Results The positive rate of cathepsin D expression in all breast cancer patients was 68.8%(110/160). Cathepsin D expression was positive correlated with that of VEGF, c-erbB-2 as well as tumor size, clinical stage and histological grade (P< 0.01), but was negati...
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