Studies on the Expression of Pten and p16 in Intraductal Papilloma and Ductal Carcinoma of Breast

Objective To explore the expression of Pten and p16 in intraductal papilloma(IDP) and ductal carcinoma of breast and to further evaluate the biological features of intraductal papilloma of breast. Methods Paraffin-embedded specimens from 23 patients with IDP and 29 patients with invasive ductal carcinoma were included in this study. The expression of Pten and p16 at protein level was examined using indirect immunofluorescent staining and flow cytometric method. Results The positive expression rates of...