Visualization Analysis of Research Hotspots and Trends in the Field of Tumor Therapy Based on CiteSpace and VOSviewer

Objective To conduct a bibliometric study in the field of cancer treatment, and to explore the research hotspots and development trends in the field of cancer treatment in the past decade. Methods We searched the Web of Science Core Collection and CNKI database for Chinese and English articles related to cancer treatment published over the last ten years. This manuscript selects the research methods of bibliometrics, and analyzes the key words clustering and time line of published documents. Results A total of 45, 455 Chinese articles and 866, 958 English articles were retrieved. Combined with the visualization analysis results and the current research dilemma of tumor treatment. We consider that the current research hotspots in the field of cancer treatment at home and abroad mainly focus on four parts: targeted therapy, immunotherapy, traditional Chinese medicine treatment and tumor new drug development. The detailed bibliometric study and the comparative analysis of Chinese and English literatures on these four parts respectively show that the research hotspots mainly focus on lung cancer, breast cancer and intestinal cancer. Research hotspots include immune checkpoint inhibitors, tumor microenvironment, drug delivery, nanoparticles, etc. Conclusion The bibliometric analysis shows the development trend and research hotspots in the field of tumor therapy, suggesting that new targeted drugs, immune efficacy improvement, multidisciplinary integration, nano-delivery, and traditional Chinese medicine innovation will be the key research directions in the field of tumor therapy in the future.