Progress of immune checkpoint inhibitors combined with anti-angiogenic drugs in the treatment of advanced non-small cell lung cancer

Aiju Zeng; Dai-yuan MA

doi:10.3971/j.issn.1000-8578.20241280

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Cancer Research on Prevention and Treatment > 0 > Accepted Manuscript > DOI: 10.3971/j.issn.1000-8578.20241280

Aiju Zeng, Dai-yuan MA. Progress of immune checkpoint inhibitors combined with anti-angiogenic drugs in the treatment of advanced non-small cell lung cancer[J]. Cancer Research on Prevention and Treatment. DOI: 10.3971/j.issn.1000-8578.20241280

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Progress of immune checkpoint inhibitors combined with anti-angiogenic drugs in the treatment of advanced non-small cell lung cancer

Aiju Zeng^{1, 2},
Dai-yuan MA^{1, 2,}

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Received Date: December 17, 2024
Revised Date: March 25, 2025
Accepted Date: March 26, 2025
Available Online: March 26, 2025

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Abstract

The use of immune checkpoint inhibitors (ICIs) improves the prognosis of patients with advanced non-small cell lung cancer (NSCLC). However, some patients still fail to benefit from them. In recent years, studies have demonstrated that the combination of antiangiogenic agents with ICIs can enhance the antitumor effect, and guidelines at home and abroad have also suggested that the combination of ICIs with antiangiogenic regimens can be used in patients with advanced NSCLC. Therefore, this article reviews the mechanism of action and the latest clinical studies on the combination of ICIs and anti-angiogenic drugs in the treatment of advanced NSCLC, with a view to providing reference for the treatment of advanced NSCLC.
- Non-small cell lung cancer,
- Immune checkpoint inhibitors,
- Anti-angiogenic drugs

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Progress of immune checkpoint inhibitors combined with anti-angiogenic drugs in the treatment of advanced non-small cell lung cancer

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Progress of immune checkpoint inhibitors combined with anti-angiogenic drugs in the treatment of advanced non-small cell lung cancer

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