| Citation: |
LIANG Tong, LIU Huajie, DA Mingxu. Metabolic Syndrome and Risk of Gastric Cancer: A Meta-analysis[J]. Cancer Research on Prevention and Treatment, 2021, 48(3): 268-273. DOI: 10.3971/j.issn.1000-8578.2021.20.0957
|
To evaluate the relation between metabolic syndrome (MetS) and gastric cancer (GC) based on a meta-analysis.
The case-control studies about the relation between MetS and GC were retrieved from CNKI, WanFang Data, VIP, CBM, Web of Science, The Cochrane Library and PubMed database. The retrieval time was from inception to June, 2020. Two researchers independently screened the literatures, extracted the data and evaluated the quality of the included studies. The meta-analysis of the included literatures was conducted by the Stata 12.0 software.
A total of six literatures, involving 43617 participants, were included. The results of meta-analysis showed that there was no statistically significant difference between GC and non-GC groups in the risk of hyperglycemia (OR=1.24, 95%CI: 0.59-2.61), hypertension (OR=1.40, 95%CI: 0.60-3.25) or MetS (OR=0.79, 95%CI: 0.44-1.39), respectively.
MetS may not be related to the risk of GC.
| [1] |
Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2018, 68(6): 394-424. doi: 10.3322/caac.21492
|
| [2] |
Yildirim Simsir I, Cetinkalp S, Kabalak T. Review of Factors Contributing to Nodular Goiter and Thyroid Carcinoma[J]. Med Princ Pract, 2020, 29(1): 1-5. doi: 10.1159/000503575
|
| [3] |
Albai O, Frandes M, Timar B, et al. Long-term Risk of Malignant Neoplastic Disorders in Type 2 Diabetes Mellitus Patients with Metabolic Syndrome[J]. Diabetes Metab Syndr Obes, 2020, 13: 1317-1326. doi: 10.2147/DMSO.S243263
|
| [4] |
Eskandari D, Khodabandehloo N, Gholami A, et al. Investigation of the association between metabolic syndrome and breast cancer patients[J]. Eur J Transl Myol, 2020, 30(1): 8776.
|
| [5] |
Lee DY, Lee TS. Associations between metabolic syndrome and gynecologic cancer[J]. Obstet Gynecol Sci, 2020, 63(3): 215-224. doi: 10.5468/ogs.2020.63.3.215
|
| [6] |
Markus E, Trestman S, Cohen Y, et al. Components of metabolic syndrome in patients with multiple myeloma and smoldering multiple myeloma[J]. BMC Cancer, 2020, 20(1): 489. doi: 10.1186/s12885-020-06976-1
|
| [7] |
Wang L, Du ZH, Qiao JM, et al. Association between metabolic syndrome and endometrial cancer risk: a systematic review and meta-analysis of observational studies[J]. Aging(Albany NY), 2020, 12(10): 9825-9839. http://med.wanfangdata.com.cn/Paper/Detail/PeriodicalPaper_PM32439832
|
| [8] |
Cao LL, Cai JH, Yue Z, et al. The Role of Serum Calcium in Assessing Metabolic Syndrome in Colorectal Cancer[J]. Ann Clin Lab Sci, 2020, 50(2): 233-240. http://www.researchgate.net/publication/341189968_The_Role_of_Serum_Calcium_in_Assessing_Metabolic_Syndrome_in_Colorectal_Cancer
|
| [9] |
Sawazaki H, Kitamura Y, Yagi K, et al. Impact of Androgen Deprivation Therapy on Non-Alcoholic Fatty Liver Disease in Patients with Prostate Cancer: A CT Evaluation[J]. Urol Int, 2020, 104(5-6): 425-430. doi: 10.1159/000507351
|
| [10] |
Zhang H, Zhu L, Bai M, et al. Exosomal circRNA derived from gastric tumor promotes white adipose browning by targeting the miR-133/PRDM16 pathway[J]. Int J Cancer, 2019, 144(10): 2501-2515. doi: 10.1002/ijc.31977
|
| [11] |
Li Z, Han H, Chang Y. Association between metabolic syndrome and the incidence of gastric cancer: a meta-analysis of cohort studies[J]. Diabetol Metab Syndr, 2019, 11: 83. doi: 10.1186/s13098-019-0478-y
|
| [12] |
Hu D, Zhang MJ, Zhang HJ, et al. Prediction of Metabolic Syndrome for the Survival of Patients With Digestive Tract Cancer: A Meta-Analysis[J]. Front Oncol, 2019, 9: 281. doi: 10.3389/fonc.2019.00281
|
| [13] |
DerSimonian R, Laird N. Meta-analysis in clinical trials revisited[J]. Contemp Clin Trials, 2015, 45(Pt A): 139-145. http://europepmc.org/articles/PMC4639420
|
| [14] |
梁晓峰, 李利娟, 刘俊田. 代谢综合征与胃癌发病风险及临床病理特征相关性的研究[J]. 中国肿瘤临床, 2019, 46(19): 986-993. doi: 10.3969/j.issn.1000-8179.2019.19.090
Liang XF, Li LJ, Liu JT. A case control study of the correlation between metabolic syndrome and gastric cancer[J]. Zhongguo Zhong Liu Lin Chuang, 2019, 46(19): 986-993. doi: 10.3969/j.issn.1000-8179.2019.19.090
|
| [15] |
Lin XH, Huang KH, Chuang WH, et al. The long term effect of metabolic profile and microbiota status in early gastric cancer patients after subtotal gastrectomy[J]. PLoS One, 2018, 13(11): e0206930. doi: 10.1371/journal.pone.0206930
|
| [16] |
Lee JY, Park NH, Song YS, et al. Prevalence of the metabolic syndrome and associated factors in korean cancer survivors[J]. Asian Pac J Cancer Prev, 2013, 14(3): 1773-1780. doi: 10.7314/APJCP.2013.14.3.1773
|
| [17] |
Shin JY, Choi YH, Song YM. Metabolic Syndrome in Korean Cancer Survivors and Family Members: A Study in a Health Promotion Center[J]. Nutr Cancer, 2015, 67(7): 1075-1082. doi: 10.1080/01635581.2015.1073752
|
| [18] |
Park W, Lee H, Kim EH, et al. Metabolic syndrome is an independent risk factor for synchronous colorectal neoplasm in patients with gastric neoplasm[J]. J Gastroenterol Hepatol, 2012, 27(9): 1490-1497. doi: 10.1111/j.1440-1746.2012.07128.x
|
| [19] |
Park MJ, Kim DH, Lim SH, et al. Features of Gastric Neoplasm Detected during the Screening Examination[J]. Gut Liver, 2007, 1(1): 33-39. doi: 10.5009/gnl.2007.1.1.33
|
| [20] |
Sherling DH, Perumareddi P, Hennekens CH. Metabolic Syndrome[J]. J Cardiovasc Pharmacol Ther, 2017, 22(4): 365-367. doi: 10.1177/1074248416686187
|
| [21] |
Szydło B, Kiczmer P, Świętochowska E, et al. Role of omentin and chemerin in metabolic syndrome and tumor diseases[J]. Postepy Hig Med Dosw(Online), 2016, 70(0): 844-849. http://www.ncbi.nlm.nih.gov/pubmed/27516571
|
| [22] |
Pourhoseingholi MA, Ashtari S, Hajizadeh N, et al. Metabolic Syndrome, Gastric Cancer Mortality and Competing Risk Survival Analysis[J]. EBioMedicine, 2017, 15: 4-5. doi: 10.1016/j.ebiom.2016.12.015
|
| [23] |
Sun L, Zhou P, Hua Q, et al. Effects of blood glucose, blood lipids and blood pressure control on recovery of patients with gastric cancer complicated with metabolic syndrome after radical gastrectomy[J]. Exp Ther Med, 2018, 15(6): 4785-4790.
|
| [24] |
Yoo H, Kim H, Lee JH, et al. Study on the Relevance of Metabolic Syndrome and Incidence of Gastric Cancer in Korea[J]. Int J Environ Res Public Health, 2019, 16(7): 1101. doi: 10.3390/ijerph16071101
|
| [25] |
Hashimoto Y, Hamaguchi M, Obora A, et al. Impact of metabolically healthy obesity on the risk of incident gastric cancer: a population-based cohort study[J]. BMC Endocr Disord, 2020, 20(1): 11. doi: 10.1186/s12902-019-0472-2
|
| [1] | WANG Ya'nan, LU Wenping, MEI Heting, CUI Yongjia, ZHUO Zhili. Risk of Recurrence or Metastasis of Breast Cancer by LNG-IUS: A Meta-analysis[J]. Cancer Research on Prevention and Treatment, 2022, 49(8): 786-791. DOI: 10.3971/j.issn.1000-8578.2022.21.1536 |
| [2] | XIA Lin, YU Guozheng, TANG Jing. Diagnostic Value of Circular RNAs for Colorectal Cancer: A Meta-analysis[J]. Cancer Research on Prevention and Treatment, 2021, 48(9): 864-870. DOI: 10.3971/j.issn.1000-8578.2021.21.0069 |
| [3] | SHAO Lihua, ZHANG Qiuning, LUO Hongtao, YANG Zhen, LIU Ruifeng, TIAN Jinhui, LI Zheng, WANG Xiaohu, YANG Kehu. Carbonions and Proton Therapy for Hepatocellular Carcinoma: A Meta-analysis[J]. Cancer Research on Prevention and Treatment, 2020, 47(5): 358-366. DOI: 10.3971/j.issn.1000-8578.2020.19.1158 |
| [4] | JIAN Yaowen, WANG Lei, Liu Ye, HE Mingyan, RANG Weiqing. A Meta-analysis of Dietary Vitamin Consumption and Risk of Hepatocellular Carcinoma[J]. Cancer Research on Prevention and Treatment, 2020, 47(2): 108-111. DOI: 10.3971/j.issn.1000-8578.2020.19.0007 |
| [5] | KUANG Yuhui, CHEN Xinju, XU Fangbiao. Meta-analysis of Efficacy and Safety of Jinlong Capsule Combined with Chemoradiotherapy on Liver Metastases[J]. Cancer Research on Prevention and Treatment, 2020, 47(1): 63-69. DOI: 10.3971/j.issn.1000-8578.2020.19.0619 |
| [6] | JIAN Yaowen, XIONG Wenjing, LIU Ye, LIU Yang, YANG Huixian, RANG Weiqing. A Meta-analysis on Relationship of Dietary Factors with Liver Cancer in Chinese Population[J]. Cancer Research on Prevention and Treatment, 2017, 44(7): 493-500. DOI: 10.3971/j.issn.1000-8578.2017.16.1465 |
| [7] | Zheng, Wang Shuyi, Xiong Bin. Meta-analysis on Association of Circulating Tumor Cells with Prognosis in Gastric Cancer[J]. Cancer Research on Prevention and Treatment, 2012, 39(09): 1139-1145. DOI: 10.3971/j.issn.1000-8578.2012.09.021 |
| [8] | Ma Jun, Nie Shengnan, Shi Benling, Zuo Wenshu. Meta Analysis on Relationship between Soyfood and Breast Cancer[J]. Cancer Research on Prevention and Treatment, 2012, 39(02): 218-221. DOI: 10.3971/j.issn.1000-8578.2012.02.025 |
| [9] | ZHENG Gang, WANG Shu-yi, XIONG Bin. Meta-analysis on Association of HER2-neu Expression with Prognosis in Gastric Cancer[J]. Cancer Research on Prevention and Treatment, 2011, 38(10): 1173-1177. DOI: 10.3971/j.issn.1000-8578.2011.10.021 |
| [10] | QIU Yue-feng, CAI Lin. Meta-analysis on Relationship between Body Mass Index and Lung Cancer Risk[J]. Cancer Research on Prevention and Treatment, 2010, 37(02): 218-222. DOI: 10.3971/j.issn.1000-8578.2010.02.025 |
This work is licensed under a Creative Commons Attribution 3.0 License.
Copyright © Editorial Department of Cancer Prevention Research 鄂公网安备 42011102005013号 鄂ICP备2022015867号
Supported by: Beijing Renhe Information Technology Co., Ltd. 
DownLoad: