Advanced Search
WANG Yuanyuan, ZHA Yong, ZHANG Siyu. Role and Mechanism of SLAMF7-SLAMF7 Signaling Pathway in Tumor Progression[J]. Cancer Research on Prevention and Treatment, 2020, 47(4): 313-316. DOI: 10.3971/j.issn.1000-8578.2020.19.1205
Citation: WANG Yuanyuan, ZHA Yong, ZHANG Siyu. Role and Mechanism of SLAMF7-SLAMF7 Signaling Pathway in Tumor Progression[J]. Cancer Research on Prevention and Treatment, 2020, 47(4): 313-316. DOI: 10.3971/j.issn.1000-8578.2020.19.1205

Role and Mechanism of SLAMF7-SLAMF7 Signaling Pathway in Tumor Progression

  • The signaling lymphocytes activating molecule factor 7(SLAMF7) is not only expressed on the surface of some malignant tumor cells, but also widely expressed in immune cells, including natural killer cells, CD4+T cells, CD8+T cells, B cells, dendritic cells (DCs) and monocytes/macrophages. It can regulate the biological behavior of tumor cells as well as immune cells and contribute to anti-tumor effects of immune cells in tumor microenvironment. Herein, we review the functional role of SLAMF7 in regulating immune cells to suppress tumor progression.
  • loading

Catalog

    Turn off MathJax
    Article Contents

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return