Recurrence-related Factors of 46 Stage Ⅰ-Ⅱ Endometrial Carcinoma Patients

Objective To investigate the risk factors of the recurrence of stage Ⅰ-Ⅱ endometrial carcinoma.

Methods We retrospectively analyzed the data of 516 patients with stage Ⅰ-Ⅱ endometrial carcinoma treated in Nanjing Drum Tower Hospital from January 2010 to December 2017. The recurrence rate of the patients was followed up.

Results The recurrence rate was 8.91%(46/516). Age, body weight, hypertension, stage of operation and pathology, pathological type, low expression of ER and PR were correlated with the recurrence of stage Ⅰ-Ⅱ endometrial carcinoma (P < 0.05). Diabetes mellitus, vascular metastasis, pathological differentiation, lymph node excision and ascites cytologic examination were not correlated with the recurrence of stage Ⅰ-Ⅱ endometrial carcinoma (P > 0.05). Age, body weight and blood pressure were independent risk factors for the recurrence of stageⅠ-Ⅱendometrial carcinoma (P < 0.05).

Conclusion Age, body weight, hypertension, stage of operation and pathology, pathological type, low expression of ER and PR affect the recurrence of stage Ⅰ-Ⅱ endometrial carcinoma. Advanced age, low body weight and hypertension are independent risk factors for the recurrence of stage Ⅰ-Ⅱ endometrial carcinoma. In clinical work, we should follow up closely stage Ⅰ-Ⅱ endometrial carcinoma patients with advanced age, low body weight and hypertension, for early detection and in-time treatment of recurrence lesions.