Application Progress of ⁶⁸Ga-PSMA PET/CT in Recurrent Prostate Cancer

The morbidity of prostate cancer (PCa) is high. Early diagnosis of recurrence after primary treatment is very important for the prognosis. Prostate specific membrane antigen (PSMA) is a transmembrane glycoprotein, with high expression in PCa. Small molecule inhibitors of the PSMA is labeled by ⁶⁸Ga(⁶⁸Ga-PSMA). ⁶⁸Ga-PSMA is used as imaging agent for PET/CT imaging. ⁶⁸Ga-PSMA PET/CT can display the distribution of prostate cancer in vivo. Many European and American countries have used ⁶⁸Ga-PSMA PET/CT to find recurrent lesions in prostate cancer patients and achieved good results. This technology is still in its initial stage in China. This article reviews the research progress of ⁶⁸Ga-PSMA PET/CT in prostate cancer recurrence, in order to improve the understanding of this new technology in China.