Advance of Prognostic Markers of Cervical Cancer

Cervical cancer is one of the most common malignancies in female, seriously affecting the health of women, particularly in developing countries. The main cause of death is local recurrence and metastasis. Therefore, the selection of reasonable treatment plans, accurate assessment of the prognosis, and reducing the recurrence and metastasis are the keys to reduce the mortality of cervical cancer. Currently the main prognostic markers of cervical cancer include FIGO stage, lymph node metastasis, interstitial infiltration, tumor size, vascular invasion, but these clinical pathological features are not accurate enough in prognosis evaluation. So, we need to find new prognostic markers to accurately guide the treatment. In recent years, molecular tumor markers had been extensively studied, and some molecular markers associated with the prognosis have been confirmed. This article reviews the current status of molecular markers related to the prognosis of cervical cancer, and aims to explore new ideas for the follow-up study and provide a more reasonable basis for the treatment of cervical cancer.